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Calcium Carbonate,Zinc & Calcitriol

This is an ideal dietary supplement for people with knee pain and is a remarkable example of nutritional science – being a delicately balanced formula to improve bone and joint health and combating debilitating bone-joint diseases. This is a perfect combination which contains Calcitriol, Calcium Carbonate, and Zinc as active ingredients. The components in combination are helping body in Low blood calcium levels in people who do not get enough calcium from their diets Conditions caused by low calcium levels such as bone loss (osteoporosis), weak bones (osteomalacia/rickets), decreased activity of the parathyroid gland (hypoparathyroidism), and a certain muscle disease (latent tetany).

  • Composition

    Calcitriol IP 0.25 mcg
    Calcium Carbonate IP 500 mg
    (Eq. to Elemental Calcium 200mg)
    Zinc 7.5 mg
    (As Zinc Sulphate Monohydrate) IP

  • Release form

    Soft gel

  • Category

    Supplement

Certain patients to make sure they are getting enough calcium (e.g., women who are pregnant, nursing, or postmenopausal, people taking certain medications such as phenytoin, phenobarbital, or prednisone). Neutralizing acids thus relieving acid reflux Regulating the intestinal fluid transport, mucosal integrity, immunity, gene expression and oxidative stress along with taking care of body's normal growth and its repair

Indications

Bone diseases in renal osteodystrophy, Dietary supplement, Bones weakening, Better absorption, Acidity & Heartburn, Stomach ulcer, Diarrhea, Wilson's disease, Acne, Age related vision loss and Anemia

Pharmacology

Calcitriol, a pharmaceutical form of vitamin D, has anti-osteoporotic, immunomodulatory, anticarcinogenic, antipsoriatic, antioxidant, and mood-modulatory activities. Calcitriol has been found to be effective in the treatment of psoriasis when applied topically. Calcitriol has been found to induce differentiation and/or inhibit cell proliferation in a number of malignant cell lines including human prostate cancer cells. Vitamin D deficiency has long been suspected to increase the susceptibility to tuberculosis. The active form of calcitriol, 1,25-(OH)2-D3, has been found to enhance the ability of mononuclear phagocytes to suppress the intracellular growth of Mycobacterium tuberculosis. 1,25-(OH)2-D3 has demonstrated beneficial effects in animal models of such autoimmune diseases as rheumatoid arthritis. It has also been found to induce monocyte differentiation and to inhibit lymphocyte proliferation and production of cytokines, including interleukin IL-1 and IL-2, as well as to suppress immunoglobulin secretion by B lymphocytes. Vitamin D appears to demonstrate both immune-enhancing and immunosuppressive effects..

Interactions

It may interact with anti-cancer medication (estramustine), Cholestyramine (cholesterol-lowering agent), Digitalis (used to treat heart problems), medicines to treat bacterial infections such as Ciprofloxacin, Levofloxacin, Gatifloxacin, Sparfloxacin, Ofloxacin; Ketoconazole (treat fungal infections).

Side Effects

  • Diseases and/or conditions resulting in hypercalcaemia and/or hypercalciuria (e.g. myeloma, bone metastases, primary hyperparathyroidism)
  • Nephrolithiasis / nephrocalcinosis
  • Severe renal impairment and renal failure
  • Hypervitaminosis D